Bioinformatics
Babraham Institute (Cambridge)
About the Project Project Title: Cross-Species determinants of stress susceptibility in PSC-derived Neural Progenitors and Spinal Motor Neurons Life unfolds at remarkably different speeds across species, yet the molecular mechanisms that regulate developmental tempo remain poorly understood.
- Location
- Cambridge, United Kingdom
- Deadline
- 8 December 2026
- Funding
- Funded PhD Project (Students Worldwide)
Biochemistry
Babraham Institute (Cambridge)
About the Project Project Title: Fantastic proteins and where to find them: exploring the biology of histones outside the nucleus Histone proteins package DNA within the confines of the nucleus in a macromolecular structure called chromatin. They additionally modulate the accessibility of DNA to gene and epigenetic regulators through the chemical modifications they carry (post-translational modifications, PTMs).
- Location
- Cambridge, United Kingdom
- Deadline
- 8 December 2026
- Funding
- Competition Funded PhD Project (Students Worldwide)
Developmental Biology
Babraham Institute (Cambridge)
About the Project Project title: Poised Chromatin and the Epigenetic Control of Development Project outline How cells switch genes on and off at the right time is fundamental to development. In embryonic stem cells, many genes whose expression is required later in development are kept in a ""poised"" state, ready to be activated during cell lineage commitment.
- Location
- Cambridge, United Kingdom
- Deadline
- 8 December 2026
- Funding
- Funded PhD Project (Students Worldwide)
Genetics
Babraham Institute (Cambridge)
About the Project Project Title : Spatial Control of Wnt–ERK Signalling by Glypican-Dependent Ligand Dispersal in Development and Disease Glypicans are a family of heparan sulfate proteoglycans that regulate extracellular signalling environments during development. Human genetics highlights the importance of this regulation: loss-of-function mutations in GPC6 cause omodysplasia, a rare skeletal dysplasia characterised by impaired growth and developmental defects.
- Location
- Cambridge, United Kingdom
- Deadline
- 8 December 2026
- Funding
- Competition Funded PhD Project (Students Worldwide)
Genomics
Babraham Institute (Cambridge)
About the Project Project Title: T cell signalling in fibrotic feedback loops Fibrosis is a pathological feature of many chronic inflammatory diseases, characterized by extracellular matrix (ECM) dysregulation, connective tissue accumulation, and complex immune-stromal feedback loops.
- Location
- Cambridge, United Kingdom
- Deadline
- 8 December 2026
- Funding
- Funded PhD Project (Students Worldwide)
Bioinformatics
Babraham Institute (Cambridge)
About the Project Project Title: The dark side of DNA Project Outline We think of DNA as a stable information source compartmentalised to the nucleus and mitochondria. When DNA enters the cytosol, it is recognised as a pathogen-associated molecular pattern by immune mechanisms that trigger inflammatory responses. However, a spectrum of diseases arise from mutations that increase formation or limit degradation of cytosolic DNA, even in the absence of infection.
- Location
- Cambridge, United Kingdom
- Deadline
- 8 December 2026
- Funding
- Funded PhD Project (Students Worldwide)