Raman ProLipMet-Omics Sub-cellular Imaging for Real-Time Therapeutic Monitoring

About the project

About the Project Applications are invited for a fully-funded three year PhD to commence in February 2027. The PhD will be based in the Faculty of Science and Health, and will be supervised by Dr Priyanka Dey , Associate Professor of Molecular Diagnostics (University of Portsmouth), and Dr Carla Newman, Associate Director in Cellular Imaging (GSK, UK). Project description The project will integrate Raman spectroscopy, mass spectrometry and in vitro sub-cellular biomolecular mapping to investigate changes in proteins, lipids and metabolites during therapeutic treatment. The project has the potential to enable non-invasive analysis of cellular responses and contribute to future developments in drug discovery, therapeutic monitoring and personalised medicine. The successful candidate will receive interdisciplinary training in cutting-edge measurement science technologies and gain experience working at the interface of molecular diagnostics, analytical chemistry, cell biology and pharmaceutical research. The candidate will work in close collaboration with GSK and the work will be split at Portsmouth and GSK Stevenage campus. General admissions criteria You'll need a good first degree from an internationally recognised university (minimum upper second class or equivalent, depending on your chosen course) or a Master’s degree in a relevant discipline, such as analytical chemistry, biochemistry, biomedical science, pharmaceutical science, molecular biology, biophysics or a related subject. In exceptional cases, we may consider equivalent professional experience and/or qualifications. English language proficiency at a minimum of IELTS band 6.5 with no component score below 6.0. Specific candidate requirements Practical laboratory experience in at least one of the following areas is desirable: Mammalian cell culture Raman spectroscopy or Raman imaging Mass spectrometry Bioanalytical or molecular characterisation techniques The ideal candidate will be highly motivated, enthusiastic about interdisciplinary research and able to work effectively with both academic and industrial collaborators. How to Apply We’d encourage you to contact Dr Priyanka Dey ( priyanka.dey@port.ac.uk ) to discuss your interest before you apply, quoting MPB50850227 - RamPLM PhD. When you are ready to apply, you can use our online application form . Make sure you submit a personal statement, proof of your degrees and grades, details of two referees, proof of your English language proficiency and an up-to-date CV. Our ‘ How to Apply ’ page offers further guidance on the PhD application process. If you want to be considered for this funded PhD opportunity you must quote project code MPB50850227 when applying

Research areas